İSTANBUL İLİNDE ÜÇ HASTANEDE AYAKTAN İZLENEN TİP II DİYABETİK HASTALARDA GLİSEMİK KONTROLÜN MALİYET ETKİNLİĞİNİN DEĞERLENDİRİLMESİ - THE COST EFFECTIVENESS of GLYCEMIC CONTROL in TYPE II DIABETIC PATIENTS UNDER FOLLOW-UP in THREE HOSPITALS in ISTANBUL

Muhammed Fatih Önsüz, Ahmet Topuzoğlu

Öz


Diyabet gittikçe artan maliyete sahip bir kronik hastalıktır. Diyabetin kontrol ve tedavisinde en önemli hedef ise glisemik kontroldür. Araştırmanın amacı; İstanbul’da hizmet veren üç ayrı hastanede ayaktan izlenen tip II diyabetik hastalarda glisemik kontrol için kullanılan tedavilerin maliyet etkililiğinin değerlendirilmesidir. Araştırma, İstanbul’da devlet, üniversite ve özel olmak üzere üç ayrı hastaneye kontrol için başvuran en az altı aylık tanılı 392 tip II diyabet hastası ile yürütülmüş bir maliyet-etkililik araştırması idi. Veriler, araştırmacılar tarafından hazırlanan iki bölümden oluşan bir anket formu uygulanarak toplandı. Maliyet etkililik analizinde her hastane için alınan tedavi türüne göre toplam maliyet ve etkililik hesaplandı. İstatistiksel analizler SPSS paket programında tanımlayıcı istatistikler ve X2 testi kullanılarak değerlendirildi. Değişkenlerin birlikte glisemik kontrolün toplam maliyetinin ne kadarını açıkladığını belirlemek amacıyla çoklu regresyon analizi kullanıldı. Araştırmaya katılan hastaların %59.2’sinin HgbA1c düzeyleri normaldi ve hastaneler arasında hastaların HgbA1c düzeyleri açısından istatistiksel olarak anlamlı fark bulundu (p<0.001). Çoklu regresyon analizinde; başvurulan hastane, hastalığın süresi, alınan tedavi türü, hastanın BKİ ve HgbA1c değeri glisemik kontrolün toplam maliyetini arttıran faktörler olarak, diyet listesini uygulama durumu ise maliyeti azaltan faktör tespit edildi. Ayrıca analiz sonucunda başvurulan hastane göreli olarak en önemli değişken olarak bulundu. Oral antidiyabetik (OD) tedavi için ise, üniversite hastanesi maliyet etkililik açısından maliyeti düşük ve etkililiği yüksek olarak bulundu ve maliyet-etkililik analizinde kabul sonucu saptandı. Tip II diyabetik hastalardaki tedavilerin etkinliği ve maliyeti her üç hastanedeki poliklinik uygulamaları açısından karşılaştırılmış ve farklı bulunmuştur.

Anahtar Kelimeler: Diabetes mellitus, Hastane, Maliyet, Maliyet etkililik

 

THE COST EFFECTIVENESS OF GLYCEMIC CONTROL IN TYPE II DIABETIC
PATIENTS UNDER FOLLOW-UP IN THREE HOSPİTALS IN ISTANBUL

Abstract:
Diabetes mellitus is a chronic disease with increasing health costs. The major target in the control and treatment of diabetes is the glycemic control. The aim of this study was to evaluate the cost-effectiveness of glycemic control in type II diabetic patients under follow-up in three hospitals in Istanbul. This is a cost-effectiveness study conducted on 392 patients with a diagnosis of type II diabetes for at least 6 months who were under follow-up in a total of three
state, university and private hospitals in Istanbul. Data were collected by using a two-section questionnaire form prepared by the researchers. Cost-effectiveness is analyzed by calculating the total cost and effectiveness by the treatment method in each hospital. Statistical analysis was performed on SPSS package program and by using descriptive statistics and X2 test. Multiple regression analysis was used to determine whether the variables can explain the total
cost of glycemic control. The HbA1c level was normal in 59.2% of the participants and differed significantly between the patients from different hospitals (p<0.001). Multiple regression analysis revealed the factors increasing the cost as the hospital admitted, disease duration, treatment type, BMI and HBA1c level, while the factor decreasing the cost was compliance to the diet list. Importantly, the relatively most significant variable was the hospital admitted. For the treatment with oral antidiabetics (OD), university hospitals had the least cost and highest effectiveness with an acceptable cost-effectiveness. Effectiveness and cost of the therapy in Type II diabetic patients were compared and found to be different between the outpatient clinics in three hospitals. 

Key words: Diabetes mellitus, Hospital, Cost, Cost-effectiveness


Tam Metin:

ARTICLE 1

Referanslar


Shaw JE, Sicree RA, Zimment PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010;87(1):4–14.

Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27(5):1047–1053.

American Diabetes Association. Economic costs of diabetes in the U.S. in 2007. Diabetes Care 2008;31(3):596–615.

Marchesini G, Forlani G, Rossi E, Berti A, De Rosa M, on behalf of the ARNO Working Group. The direct economic cost of pharmacologically-treated diabetes in Italy-2006. The ARNO Observatory. Nutr Metab Cardiovasc Dis 2011;21(5):339-346.

Jonsson B, CODE-2 Advisory Board. Revealing the cost of type II diabetes in Europe. Diabetologia 2002;45:S5-12.

Ohinmaa A, Jacobs P, Simpson S, Johnson JA. The projection of prevalence and cost of diabetes in Canada: 2000 to 2016. Canadian Journal of Diabetes 2004;28(2):1-8.

Rathmann W, Haastert B, Icks A, Guido G. Trends in outpatient prescription drug costs in diabetic patients in Germany, 1994–2004. Diabetes Care 2007;30:848–853.

Zhang P, Zhang X, Brown J, Vistisen D, Sicree R, Shaw J, et al. Global healthcare expenditure on diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010;87:293-301.

American Diabetes Association. Standards of medical care in diabetes-2010. Diabetes Care 2010;33(Suppl 1):S11-61.

Holman RR, Paul SK, Bethel MA, Neil HA, Matthews DR. Long-term follow-up after tight control of blood pressure in type 2 diabetes. N Engl J Med 2008;359:1565–1576.

Kearney PM, Blackwell L, Collins R, Keech A, Simes J, Peto R, et al. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet 2008;371:117–125.

Ray KK, Seshasai SR, Wijesuriya S, Sivakumaran R, Nethercott S, Preiss D, et al. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials. Lancet 2009;373:1765–1772.

Wagner EH, Sandhu N, Newton KM, McCulloch DK, Ramsey SD, Grothaus LC. Effect of improved glycemic control on health care costs and utilization. JAMA 2001;285(2):182-189.

Menzin J, Langley-Hawthorne C, Friedman M, Boulanger L, Cavanaugh R. Potential short-term economic benefits of improved glycemic control: a managed care perspective. Diabetes Care 2001;24(1):51-55.

Gilmer TP, O’Connor PJ, Rush WA, Crain AL, Whitebird RR, Hanson AM, et al. Predictors of health care costs in adults with diabetes. Diabetes Care 2005;28(1):59-64.

Shetty S, Secnik K, Oglesby AK. Relationship of glycemic control to total diabetes-related costs for managed care health plan members with type 2 diabetes. J Manag Care Pharm 2005;11(7):559-564.

Oglesby AK, Secnik K, Barron J, Al-Zakwani I, Lage MJ. The association between diabetes-related medical costs and glycemic control: a retrospective analysis. Cost Eff Resour Alloc 2006;4:1.

Kalaycıoğlu S, Kardam F, Tüzün S, Ulusoy M. Türkiye için bir sosyoekonomik statü ölçütü geliştirme yönünde yaklaşım ve denemeler. Toplum ve Hekim 1998;13(2):126-137.

American Diabetic Association. Standards of medical care in diabetes-2006. Diabetes Care 2006;29(Suppl 1):S4-42.

Davis WA, Knuiman MW, Hendrie D, Davis TME. Determinants of diabetes-attributable non–blood glucose–lowering medication costs in type 2 diabetes the Fremantle Diabetes Study. Diabetes Care 2005;28:329–336.

Menzin J, Korn JR, Cohen J, Lobo F, Zhang B, Friedman M, et al. Relationship between glycemic control and diabetes-related hospital costs in patients with type 1 or type 2 diabetes mellitus. Manag Care Pharm 2010;16(4):264-275.

Redekop WK, Koopmanschap MA, Rutten GEHM, Wolffenbuttel BHR, Stolk RP, Niessen LW. Resource consumption and costs in Dutch patients with type 2 diabetes mellitus. Results from 29 general practices. Diabet Med 2002;19:246-253.

Khowaja LA, Khuwaja AK, Cosgrove P. Cost of diabetes care in out-patient clinics of Karachi, Pakistan. BMC Health Services Research 2007;7:189.

Jacobs-Van Der Bruggen MAM, Bos G, Bemelmans WJ, Hoogenveen RT, Vijgen SM, Baan CA. Lifestyle interventions are cost-effective in people with different levels of diabetes risk results from a modeling study. Diabetes Care 2007;30:128-34.

Saaddine BJ, Cadwell B, Gregg EW, Engelgau MM, Vinicor F, Imperatore G, et al. Improvements in diabetes processes of care and intermediate outcomes: United States, 1988–2002. Ann Intern Med 2006;144:465-474.

Thompson WW, Wang H, Xie M, Kolassa J, Rajan M, Tseng CL, et al. Assessing quality of diabetes care by measuring longitudinal changes in hemoglobin A1c in the veterans health. Health Services Research 2005;40:1819-1835.

Vallet T, Koivisto VA, Reunanen A, Kangas T, Rissanen A. Glycemic control in patients with diabetes in Finland. Diabetes Care 1999;22(4):575-579.

T.C. Sağlık Bakanlığı Refik Saydam Hıfzıssıhha Mektebi Müdürlüğü, Başkent Üniversitesi. Ulusal Hastalık Yükü ve Maliyet Etkililik Final Raporu. Ankara:2004.


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